Application examples for temperature control and live-cell imaging

What if any temperature-dependant mechanism could be controlled under the microscope.? Ultra-fast temperature changes could thus lead to unprecedented observations.

LEARN MORE ON OUR FAST HEATER/COOLER FOR MICROSCOPY

Thermosensitive mutations

CDC25 protein dynamic control of microtubules

Get full benefit from thermosentitive mutations. With our system capable of shifting in seconds between two temperatures, you can have the ideal ON/OFF system and a real-time observation of the cellular consequences.

Cell cycle control

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The cell cycle is temperature-dependant. Controlling cell division can greatly help understanding each single step of the cycle. Our CherryTemp technology allows you to “play” with division on live.

 

Cytoskeleton dynamics

temperature-control-cytoskeleton-dynamics2

Cytoskeleton components such as microtubules are dynamically answering to temperature. With a system allowing fast cold chocs in a reversible manner, you can observe consequences on the cellular architecture.

 

Protein trafficking

temperature-control-of-protein-trafficking3

What if you were able to slow down protein assembly at the membrane? Live-imaging of protein trafficking at the membrane or within the cell while dynamically controlling temperature can lead to unprecedented conclusions.

Heat shock responses

heat-shock-protein-live-cell-imaging

Several processes are answering to heat shocks. A system able to quickly raise temperature and unblock such processes can be of first importance while doing live-cell imaging.

 

Ion channels

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With its precise and ultra-fast temperature switch, CherryTemp offers you the possibility to activate thermo-sensitive ion channels while visualizing the downstream cellular effects with microscopy.

 

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