4Dcell

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4Dcell logo

4Dcell logo

Board members

Cyril Cerveau

Cyril Cerveau

Chief Executive Officer

Maëlle Le Berre

Maëlle Le Berre

CSO & CTO

Short Description

4Dcell offers technologies and microfluidic solutions for cellular microenvironment control. Those are the result of years of study by qualified and prestigious laboratories dedicated to cell biology and microfluidics.

Redefining cell culture, the aim is to build most up-to-date tools for cell culture, available to all. 4Dcell products are adapted to specific needs, simple to use, accessible without prior expertise, and cost effective. 4Dcell deep knowledge of both cell biology, biophysics and microfabrication techniques and our close collaboration with the best labs in the field made it possible.

4D cell location

4D cell location

Products

4Dcell produces it own kit:  Micropatterning Kit, Microchannel Kit, a cell confiner and accessories to make the researcher’s life easier!

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Noticeable publications

Actin flows mediate a universal coupling between cell speed and cell persistence

Maiuri P, Piel M. et al. Cell. 2015 Apr 9;161(2):374-86.

ESCRT-III assembly and cytokinetic abscission are induced by tension release in the intercellular bridge

Lafaurie-Janvore J, Piel M et al. Science. 2013 Mar 29;339(6127):1625-9.

Triggering cell adhesion, migration or shape change with a dynamic surface coating

Van Dongen SF, Piel M. et al. Adv Mater. 2013 Mar 25;25(12):1687-91.

External forces control mitotic spindle positioning

Fink J, Piel M. et al. Nat Cell Biol. 2011 Jun 12;13(7):771-8.

Protein micropatterns: A direct printing protocol using deep UVs

Azioune A, Piel M. et al. Methods Cell Biol. 2010;97:133-46.

Simple and rapid process forsingle cell micropatterning

Azioune A, Piel M. et al. Lab Chip. 2009 Jun 7;9(11):1640-2

Mechanisms for fast cell migration in complex environments

Vargas P, Piel M. et al., Curr Opin Cell Biol. 2017 Jun 19;48:72-78.

Study of dendritic cell migration using micro-fabrication.

Vargas P, Lennon-Dumenil AM. Et al., J Immunol Methods. 2016 May;432:30-4.

ESCRT III repairs nuclear envelope ruptures during cell migration to limit DNA damage and cell death.

Raab M, Piel M. et al., Science. 2016 Apr 15;352(6283):359-62.

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