InSphero

Visit InSphero's website (click on the logo)

Insphero logo

Insphero logo

Board members

Jan Lichtenber

Jan Lichtenber

Chief Executive Officer | Co-founder

Jens M. Kelm

Jens M. Kelm

Chief Technology Officer

Patrick Guve

Patrick Guve

Chief Scientific Officer

Olivier Krähenbühl

Olivier Krähenbühl

Chief Financial Officer

Melanie Aregger

Melanie Aregger

Chief Operating Officer

Wolfgang Moritz

Wolfgang Moritz

Head of Research and Applications | Cofounder

Short Description

InSphero provides in vitro testing with easy-to-use solutions for production, culture and assessment of more organotypic 3D cell culture models.  InSphero patented 3D cell culture platforms and methods that enable large-scale, reproducible production of a broad range of assay-ready deriving from liver, pancreas, tumor, heart, brain, and skin.  These models help to identify promising drugs and toxic liabilities with greater predictivity at early development stages, enabling better pre-clinical decision making, saving development cost, and shortening time to market.  Microtissues are available directly or through a menu services, supported by a comprehensive panel of 3D-optimized culture media, assay protocols, and imaging solutions.  This 3D know-how is being applied in the diagnostics field to aid development of personalized chemotherapeutic strategies for the treatment of cancer.

Insphero location

Insphero location

Products

InSphero is commercializing 3D micro tissue model of different organs in different species. They also commercialize kits to mimic diseases. Finally, they provide services for toxicological assessment and drug discovery.

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Noticeable publications

– Hepatic 3D spheroid models for the detection and study of compounds with cholestatic liability.  Sci Rep. 2016

– High-throughput imaging: Focusing in on drug discovery in 3D. Methods. 2016

– Multifunctional in vivo imaging of pancreatic islets during diabetes development. Development. 2016

-Development and Characterization of a Scaffold-Free 3D Spheroid Model of Induced Pluripotent Stem Cell Derived Human Cardiomyocytes. Tissue Eng Part C Methods. 2015

– Adding the “heart” to hanging drop networks for microphysiological multi-tissue experiments. Lap Chip.2015

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