The TPLATE complex mediates membrane bending during plant clathrin-mediated endocytosis
Introduction While plant CME is actin independent, the authors identify that the 4 evolutionarily ancient octameric
Archive
Cell lineage-dependent chiral actomyosin flows drive cellular rearrangements in early Caenorhabditis elegans development
Early cell divisions of the AB lineage, but not of the P/EMS lineage, undergo chiral counter-rotating
Organ-on-chip applications in drug discovery: an end-user perspective
Introduction Organ-on-a-chip is regarded as a key new technology for research and development because it can
Advanced models of human skeletal muscle differentiation, development and disease: 3D cultures, organoids and beyond
Introduction The organization and function of living muscle tissues cannot be fully recapitulated by typical two-dimensional
Kidney Organoid and Microphysiological Kidney Chip Models to Accelerate Drug Development and Reduce Animal Testing
Introduction Kidney Organoid and Microphysiological Kidney Chip Models, both have their own unique advantages and deficiencies.
Beyond Polydimethylsiloxane (PDMS): Alternative Materials for Fabrication of Organ-on-a-Chip Devices and Microphysiological Systems
Introduction PDMS, often known as dimethylpolysiloxane or dimethicone, is a silicone polymer. There are various uses
Pharmacokinetics-On-a-Chip: In Vitro Microphysiological Models for Emulating of Drugs ADME
Introduction Drug compounds’ effectiveness, toxicity, and pharmacokinetics may be more accurately predicted in humans with the
Liver microphysiological platforms for drug metabolism applications
Introduction Liver microphysiological platforms for drug metabolism applications are the need of the hour to fix
Adipose Tissue-Endothelial Cell Interactions in Obesity-Induced Endothelial Dysfunction
Introduction Adipose tissue progenitor cells directly interact with endothelial cells to induce vascular network formation. Adipose
A versatile microfluidic tool for the 3D culture of HepaRG cells seeded at various stages of differentiation
Introduction Recently, microfluidics and 3D cell culture technologies have merged, to increase the potential of in
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