Advanced models of human skeletal muscle differentiation, development and disease: 3D cultures, organoids and beyond
Introduction The organization and function of living muscle tissues cannot be fully recapitulated by typical two-dimensional
Organs-on-a-chip
Kidney Organoid and Microphysiological Kidney Chip Models to Accelerate Drug Development and Reduce Animal Testing
Introduction Kidney Organoid and Microphysiological Kidney Chip Models, both have their own unique advantages and deficiencies.
Beyond Polydimethylsiloxane (PDMS): Alternative Materials for Fabrication of Organ-on-a-Chip Devices and Microphysiological Systems
Introduction PDMS, often known as dimethylpolysiloxane or dimethicone, is a silicone polymer. There are various uses
Pharmacokinetics-On-a-Chip: In Vitro Microphysiological Models for Emulating of Drugs ADME
Introduction Drug compounds’ effectiveness, toxicity, and pharmacokinetics may be more accurately predicted in humans with the
Liver microphysiological platforms for drug metabolism applications
Introduction Liver microphysiological platforms for drug metabolism applications are the need of the hour to fix
A versatile microfluidic tool for the 3D culture of HepaRG cells seeded at various stages of differentiation
Introduction Recently, microfluidics and 3D cell culture technologies have merged, to increase the potential of in
A new microfluidic method enabling the generation of multi-layered tissues-on-chips using skin cells as a proof of concept (Valencia et al, 2021)
Introduction Every organ is composed of a mesenchymal (stroma) and a parenchymal fraction. Conventional two-dimensional (2D)
Rebuilding the Vascular Network: In vivo and in vitro Approaches (Meng et al, 2021)
Introduction The vascular network carries the transportation of materials and nutrients as the fluid delivery mechanism
Experimental liver models: from cell culture techniques to microfluidic organs-on-chip (Polidoro et al, 2021)
Introduction – The Organ-on-a-Chip (OOAC) is a leading organ biomimetic (POB) device based on a microfluidic
Review on the Vascularization of Organoids and Organoids-on-a-Chip (Xingli and Zilu et al, 2021)
Introduction Organoids and organs-on-a-chip (vascularized 3d culture) have seen rapid growth in recent years due to
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