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An easy-to-build and re-usable microfluidic system for live-cell imaging
Summary | Background Real-time monitoring of cellular responses to dynamic changes in their environment or to specific treatments has become central to cell biology. However, when ...
Read moreReal-time qPCR using CherryTemp on-a-chip
(Lab on Chip, 2016) Summary | To control future infectious disease outbreaks, like the 2014 Ebola epidemic, it is necessary to develop ultrafast molecular assays enabling ...
Read morePhospho-regulated interaction between kinesin-6 Klp9p and microtubule bundler Ase1p promotes spindle elongation.
(Developmental cell, 2009) Summary | The spindle midzone—composed of antiparallel microtubules, microtubule-associated proteins (MAPs), and motors—is the structure responsible for microtubule organization and sliding during anaphase ...
Read moreFast microfluidic temperature control during high resolution live cell imaging
(Lab on Chip, 2011) Summary | One major advantage of using genetically tractable model organisms such as the fission yeastSchizosaccharomyces pombe is the ability to construct temperature-sensitive ...
Read moreImaging of mitochondria positioning using fast temperature regulation
(Current Biology, 2011) Summary | Mitochondria form a dynamic tubular network within the cell. Proper mitochondria movement and distribution are critical for their localized function in ...
Read moreFast temperature controller for live-cell imaging cytoskeleton studies
(Methods in Cell biology, 2010) Summary | Recent development in soft lithography and microfluidics enables biologists to create tools to control the cellular microenvironment. One such ...
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