A temperature precision technology fitting both upright and inverted configurations

Fits upright and inverted microscopes

A same platform with a customized integration on yourmicroscope.

Compatible with any microscope

Customized items to fit Leica, Nikon, Olympus Zeiss or Deltavision scopes

Share CherryTemp between microscopes

Move the platform easily from one microscope to another

Inverted configuration2

INVERTED CONFIGURATION

Upside down transparent chip

Upright configuration2

UPRIGHT CONFIGURATION


CherryTemp Heater/Cooler for live-cell imaging

This temperature control plateform is perfectly suited for live-cell imaging experimentations.

  • Ultra-fast temperature shifts in the 5-45°C range.
  • Room temeperature fluctuations monitoring and oil objective compensation
  • High level of precision (0.1°c)
  • Plug and play

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Heat and cool down your samples in the 5 to 45°C range

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Applications notes

Scientifics notes

Use of temperature sensitive SV40 large T antigen for conditional cell line transformation

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Use of temperature sensitive SV40 large T antigen for conditional cell line transformation

Temperature control of S. pombe cytokinesis

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Temperature control of S. pombe cytokinesis

S. Pombe : Temperature control of microtubules assembly

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S. Pombe : Temperature control of microtubules assembly

Temperature control and live-cell imaging

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Temperature control and live-cell imaging

Drosophila Melanogaster and temperature control

Drosophila Melanogaster Drosophila melanogaster is a species of fly, in the taxomic order of Diptera, which belongs to the Drosophilidae...
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Drosophila Melanogaster and temperature control

The importance of seal chambers to avoid evaporation while doing live-cell imaging with thermalization

Evaporation as a major issue for long-term imaging The majority of live-cell imaging experiments done by biologist require long-term analyses....
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The importance of seal chambers to avoid evaporation while doing live-cell imaging with thermalization

C. elegans, the need of controlling temperature

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C. elegans, the need of controlling temperature

Gradients generation for cell biology in microfluidics

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Gradients generation for cell biology in microfluidics

Human cells: pH monitoring in microfluidics

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Human cells: pH monitoring in microfluidics

Membranes integrated in microfluidic devices

Yizhe Zheng, Wen Dai, Declan Ryan, and Hongkai Wu, Fabrication of freestanding, microperforated membranes and their applications in microfluidics, Biomicrofluidics, 2010...
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Membranes integrated in microfluidic devices

Human cells: Microfluidics as a tool for drug delivery

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Human cells: Microfluidics as a tool for drug delivery

C. elegans immobilization via microfluidics: a short review

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C. elegans immobilization via microfluidics: a short review

Human cells: Cellular metabolism

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Human cells: Cellular metabolism

C. elegans asymmetric cell division

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C. elegans asymmetric cell division

Human cells: Cell cycle temperature control

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Human cells: Cell cycle temperature control

Cell lines: Vesicular trafficking

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Cell lines: Vesicular trafficking

C. elegans temperature-sensitive mutants

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C. elegans temperature-sensitive mutants

Tracking viral entry

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Tracking viral entry

Yeast: Cell cycle and thermosensitive mutations

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Yeast: Cell cycle and thermosensitive mutations

Ion channels experiment

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Ion channels experiment
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Methods

Publications

C. elegans oocytes & chromosome segregation: microtubule pushing

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C. elegans oocytes & chromosome segregation: microtubule pushing

Inhibition of microtubule assembly using fast temperature changes

(Development, 2017) Summary | In most species, oocytes lack centrosomes. Accurate meiotic spindle assembly and chromosome segregation – essential to prevent...
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Inhibition of microtubule assembly using fast temperature changes

Medium renewal and temperature control for live-cell imaging

(Open Biology, 2016) Summary | Monitoring cellular responses to changes in growth conditions and perturbation of targeted pathways is integral to...
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Medium renewal and temperature control for live-cell imaging

Real-time qPCR using CherryTemp on-a-chip

(Lab on Chip, 2016) Summary | To control future infectious disease outbreaks, like the 2014 Ebola epidemic, it is necessary to...
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Real-time qPCR using CherryTemp on-a-chip

Temperature control of thermosensitive protein regulation

(Developmental cell, 2009) Summary | The spindle midzone—composed of antiparallel microtubules, microtubule-associated proteins (MAPs), and motors—is the structure responsible for microtubule...
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Temperature control of thermosensitive protein regulation

Fast microfluidic temperature control during high resolution live cell imaging

(Lab on Chip, 2011) Summary | One major advantage of using genetically tractable model organisms such as the fission yeastSchizosaccharomyces pombe is...
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Fast microfluidic temperature control during high resolution live cell imaging

Imaging of mitochondria positioning using fast temperature regulation

(Current Biology, 2011) Summary | Mitochondria form a dynamic tubular network within the cell. Proper mitochondria movement and distribution are critical...
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Imaging of mitochondria positioning using fast temperature regulation

Fast temperature controller for live-cell imaging cytoskeleton studies

(Methods in Cell biology, 2010) Summary | Recent development in soft lithography and microfluidics enables biologists to create tools to control...
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Fast temperature controller for live-cell imaging cytoskeleton studies
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