AIMS
→ Tumor(s) cells sequential exposure to compounds in different wells (drugs, antibodies, reagents)
→ Maintain automatic perfusion at a constant flow rate
→ Live optical readouts acquisition (fluorescence)
FEATURES
→ Temperature : 37°C
→ Gas : normoxia
→ Perfusion mode : pulse
→ Culture unit : 24 well multi well
RESULTS
→ Different medium culture circuits in multiple well, following customizable patterns
→ Cell & biopsies cultures maintained for 1 week
→ Cell tracking (contrast or fluorescence)
PERSPECTIVE
→ Endocrine disruptors and nephrotoxic compounds testing and characterization
→ Extended to 3 weeks of culture for long term/chronic effect