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Alternative to PDMS: a new biocompatible polymer for microfuidics

PDMS and its limitations to microfluidic applications

One of the bottlenecks in the development of an organ-on-a-chip is the material that will be used for the chip. The most commonly used polymer is the so-called PDMS (polydimethylsiloxane). This material display very interesting properties such as biocompatibility, flexibility, and good mechanical properties, making it a standard in labs for microfluidics. Although PDMS is a very good and practical solution while a small number of units are needed, industrialization and scaling up steps are hard to handle with this polymer. Furthermore, PDMS is known to absorb small apolar molecules and to release them afterward, which is a big issue in a toxicological study context.

Fig 1: PDMS polymer microfluidic chip

Fig 1: PDMS polymer microfluidic chip

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Bibliography/Sources

For further information take a look at the following published paper (doi. 10.1039/C7LC00488E)

FlexdymTM Polymer – https://eden-microfluidics.com/eden-materials-2/

 

To learn more head over to our innovation website for Cubix – Alternative to PDMS

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