CubiX platform —
A Complex Representation of Human Biology

The only microenvironment controller fully compatible with live imaging. It enables mimicking physiological and pathological culture conditions in vitro. Scalable, highly customisable and user-friendly.

CubiX platform includes a control unit (software, gas & flow controller), a heating stage & microfluidics perfusion lid(s).

Applications

Differentiated Endothelium

DIFFERENTITATED ENDOTHELIUM

High throughput organoids in a well

HIGH THROUGHPUT ORGANOIDS IN A WELL

FULLY DIFFERENTIATED VASCULARIZED & IMMUNOCOMPETENT SKIN

FULLY DIFFERENTIATED VASCULARIZED & IMMUNOCOMPETENT SKIN

FULLY DIFFERENTIATED SKIN & METASTATIC MELANOMA

FULLY DIFFERENTIATED SKIN & METASTATIC MELANOMA

Blood brain barrier

BLOOD BRAIN BARRIER

Liver co-culture model

3D Liver Co-Culture

Ebook download - Cubix applications

download the complete applications of CubiX - Microphysiological platform

CubiX platform - Overview

 

 

CubiX platform is designed to be highly compatible and user friendly for researchers. The platform can be setup through 4 main steps:

Step 1: Set up the parameters

CubiX back channels

Configure temperature, oxygen, flow rate, and pH levels for the CubiX microphysiological system to create the desired experimental conditions.

Step 2: Secure the perfusion lid

Transform the standard multiwell configuration into a perfusion dynamic system by securely closing the perfusion lid.

Organ-on-Well for 24 multiwell

Step 3: click and play

CubiX medium bottles

Easily switch between up to 4 different experimental conditions with simple clicks, allowing seamless experimentation.

Step 4: Live Imaging and Data Acquisition

Observe and collect real-time data through live imaging to monitor the physiological responses and outcomes of the experiments and drug testing performed in CubiX.

CubiX for resarchers

Specifications

Specifications - CubiX Platform

FAQ

The manifold is recommended for a single use, one per experiment for the best performance

All the material of the manifold has been selected for optimal live imaging compatibility. The manifold adapt onto any inverted microscope able to image a standard multiwell plate

The dead volume in the manifold’s channel is in the range 100 to 1000µl (depending on the manifold configuration). This is not counting the volume of medium in external tubing and inside the well.

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