THE GENETICS OF CAENORHABDITIS ELEGANS (1974)
Brenner shed light on the Caenorhabditis elegans in 1974 with his study demonstrating the model organism it could be. The worm had many advantages: small size (and genome), rapid life cycle, sexual system of self-fertilization making easy to isolate recessive mutants on all chromosomes which made him a favorable organism for genetical analysis and more. [1]
Toward a physical map of the genome of the nematode Caenorhabditis elegans (1986)
With the goal of obtaining a map of the C. elegans genome, Jonh Sulsoton, a Brenner student, and his collaborators worked on the sequencing and asked researchers working on C. elegans to obtain as much genome data as possible. [2]
The structure of the nervous system of the nematode Caenorhabditis elegans (1986)
Sydney Brenner was fascinated by nervous system wired, in 1986 with other searchers, he gave a picture of the organization of the nervous system in a Caenorhabditis elegans hermaphrodite including its 302 neurons. [3]
Ian Chin-Sang. Development of C. elegans.
Retrieved from : https://bit.ly/3hsmlDs
Through his research, he has advanced science and put forward a model organism that has become one of the most widely used. He has won a Nobel Prize for “his discoveries concerning genetic regulation of organ development and programmed cell death.”
Thanks to Sydney Brenner. (1927-2019)
[1] https://www.genetics.org/content/genetics/77/1/71.full.pdf
[2] https://www.pnas.org/content/pnas/83/20/7821.full.pdf
[3] http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.715.1812&rep=rep1&type=pdf
Discover the Cherry Temp
Fast temperature shift during live cells imaging device
