Tribute to C. elegans Nobel Prize : Sydney Brenner


Brenner shed light on the Caenorhabditis elegans in 1974 with his study demonstrating the model organism it could be. The worm had many advantages: small size (and genome), rapid life cycle, sexual system of self-fertilization making easy to isolate recessive mutants on all chromosomes which made him a favorable organism for genetical analysis and more. [1]

Toward a physical map of the genome of the nematode Caenorhabditis elegans (1986)

With the goal of obtaining a map of the C. elegans genome, Jonh Sulsoton, a Brenner student, and his collaborators worked on the sequencing and asked researchers working on C. elegans to obtain as much genome data as possible. [2]

The structure of the nervous system of the nematode Caenorhabditis elegans (1986)

Sydney Brenner was fascinated by nervous system wired, in 1986 with other searchers, he gave a picture of the organization of the nervous system in a Caenorhabditis elegans hermaphrodite including its 302 neurons. [3]


Ian Chin-Sang. Development of C. elegans.

Retrieved from :

Through his research, he has advanced science and put forward a model organism that has become one of the most widely used. He has won a Nobel Prize for “his discoveries concerning genetic regulation of organ development and programmed cell death.”

Thanks to Sydney Brenner. (1927-2019)





Discover the Cherry Temp

Fast temperature shift during live cells imaging device