Intestinal Biopsies Beyond Histological Diagnosis: Ex-vivo Culturing and Precision Cut Slices for Precision Pharmacology

Intestine: Overview, Histology and Pathology 

The intestine is the largest part of the alimentary canal, which is part of the gastrointestinal tract (also called ‘gut’) that, with accessory glands, form the digestive system. The intestine is divided in small intestine (duodenum, jejunum, and ileum) and large intestine (cecum, colon, rectus, and anus). The small intestine is where most of the digestion and absorption occurs; the large intestine completes the absorption of nutrients and water, synthesise certain vitamins, produce faeces, and excrete the substances eliminated from the body.

The intestinal histology, including the histology of small and large intestine, is described in figure 1.

intestinal-biopsies

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