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Tumor Hypoxia and metastasis

Solid tumors are characterized by areas of hypoxic tissue heterogeneously distributed inside the tumor mass. Hypoxia triggers tumor aggressivity, as it tends to select ...

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Tumor microenvironment (TME)

The tumor microenvironment (TME) is a complex biochemical network which includes multiple factors surrounding tumor cells, such as vascular networks, the extracellular matrix (ECM), ...

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Microtubule depolymerization by cold

Microtubules (MT) are involved in multiple cellular processes, including mitosis, cell transport, morphogenesis and motility. Two populations of microtubules have been described: cold labile ...

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