Three-tissue microphysiological system for studying inflammatory responses in gut-liver Axis
Introduction The gut-liver axis is the bidirectional interaction that exists between the gut and its microbiota,
Scientific Notes
Low-cost rapid prototyping and assembly of an open microfluidic device for a 3D vascularized organ-on-a-chip
Introduction In vitro generation of perfusable 3D microvessels is an important goal for tissue engineering and
Co-culture With Human Breast Adipocytes Differentially Regulates Protein Abundance in Breast Cancer Cells
Introduction In postmenopausal women, fat mass and adipose-tissue mass (see Human Breast Adipocytes) are closely linked to obesity
Organ-on-Chips for Studying Tissue Barriers: Standard Techniques and a Novel Method for Including Porous Membranes Within Microfluidic Devices
Introduction Organ-on-Chips for Studying Tissue Barriers – Disruption of cell-formed tissue barriers is an essential part of
Isolation, Integration, and Culture of Human Mature Adipocytes Leveraging Organ-on-Chip Technology
Introduction Obesity and obesity-related co-morbidities are on the rise globally, necessitating the development of novel treatments. White
A Microfluidic 3D Endothelium-on-a-Chip Model to Study Transendothelial Migration of T Cells in Health and Disease
Introduction Microfluidic 3D Endothelium-on-a-Chip – The endothelium is a thin membrane that lines the heart and
3D Microphysiological System- Vascularized Tissue Constructs for Regenerative Medicine
Introduction Human vascular microphysiological systems (MPS) represent promising three-dimensional in vitro models of normal and diseased vascular tissue.
Organ-on-a-Chip: A New Paradigm for Drug Development
Introduction Organ-on-a-Chip is a potential, multidisciplinary method for in-vitro modeling of disease, drug screening, and precision
A Review of Biomaterials and Scaffold Fabrication for Organ-on-a-Chip Systems
Introduction Biomaterial scaffold like the extracellular matrix (ECM) is the non-cellular component of an organ on
Adipocyte-Endothelium Crosstalk in Obesity
Introduction The supporting vasculature is critical to the development of Adipose Tissue (AT) engineered models. Although it is
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