Low-cost rapid prototyping and assembly of an open microfluidic device for a 3D vascularized organ-on-a-chip
Introduction In vitro generation of perfusable 3D microvessels is an important goal for tissue engineering and
Scientific Notes
Co-culture With Human Breast Adipocytes Differentially Regulates Protein Abundance in Breast Cancer Cells
Introduction In postmenopausal women, fat mass and adipose-tissue mass (see Human Breast Adipocytes) are closely linked to obesity
Organ-on-Chips for Studying Tissue Barriers: Standard Techniques and a Novel Method for Including Porous Membranes Within Microfluidic Devices
Introduction Organ-on-Chips for Studying Tissue Barriers – Disruption of cell-formed tissue barriers is an essential part of
Isolation, Integration, and Culture of Human Mature Adipocytes Leveraging Organ-on-Chip Technology
Introduction Obesity and obesity-related co-morbidities are on the rise globally, necessitating the development of novel treatments. White
A Microfluidic 3D Endothelium-on-a-Chip Model to Study Transendothelial Migration of T Cells in Health and Disease
Introduction Microfluidic 3D Endothelium-on-a-Chip – The endothelium is a thin membrane that lines the heart and
3D Microphysiological System- Vascularized Tissue Constructs for Regenerative Medicine
Introduction Human vascular microphysiological systems (MPS) represent promising three-dimensional in vitro models of normal and diseased vascular tissue.
Organ-on-a-Chip: A New Paradigm for Drug Development
Introduction Organ-on-a-Chip is a potential, multidisciplinary method for in-vitro modeling of disease, drug screening, and precision
A Review of Biomaterials and Scaffold Fabrication for Organ-on-a-Chip Systems
Introduction Biomaterial scaffold like the extracellular matrix (ECM) is the non-cellular component of an organ on
Adipocyte-Endothelium Crosstalk in Obesity
Introduction The supporting vasculature is critical to the development of Adipose Tissue (AT) engineered models. Although it is
The vascular niche in next generation microphysiological systems
Introduction The phrase ‘vascular niche’ refers to a region rich in blood arteries where endothelial cells
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