Despite the major advances in anticancer therapies in the last few decades, cancer remains a deadly disease.
Tumor cells develop adaptative mechanisms allowing them to survive, including genetic and epigenetic modifications, alterations in the tumor microenvironment (TME), metabolic changes and apoptosis resistance.
The function of the immune system is to target and eliminate pathogens and abnormally proliferating cells from the human body. The immune system can recognize cancer cells and can have an effect on their proliferation through tumor surveillance. Therefore, a promising strategy for cancer therapy is the use of the patient immune system to target cancer cells. These strategies include In vitro activation and expansion of the immune cells to use in patients.
This section contains Scientific Notes reviewing cancer and immuno-oncology related topics
The sum of the next-generation 3D cells culture technologies