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Automated phenotyping of Caenorhabditis elegans embryos with a high-throughput-screening microfluidic platform
A new microfluidic system allows the high throughput phenotyping of C. elegans embryos! Martin A. M. Gijs et al. produced a high-throughput multiplexed microfluidic platform ...
Read moreRoles of actin in the morphogenesis of the early Caenorhabditis elegans embryo
Ever look for info about the roles of actin in asymmetric cell division? Everything is reviewed here for C. elegans embryo Actin is one of ...
Read moreUsing the Four-Cell C. elegans Embryo to Study Contractile Ring Dynamics During Cytokinesis
Discover new in vivo protocols to understand contractile ring dynamics during cytokinesis in C. elegans embryo Fung Yi Chan, Ana Marta Silva, and Ana Xavier Carvalho elaborated several experimental ...
Read moreSingle-Cell Protein Atlas of Transcription Factors in C. elegans embryo
For the first time Zhuo Du et al. correlate mRNA and protein expression in C. elegans embryo to build the first embryo protein mapping. After ...
Read moreA Waddington Epigenetic Landscape for the C. elegans embryo
C.elegans embryonic development uses redundant genes and are epigenetically shaped by parental adaptations to survive. Conrad Hal Waddington (1905-1975) developed his “Waddington Epigenetic Landscape” model ...
Read moreThe daf-2 insulin receptor functions in C. elegans embryo elongation
Role of Daf-2 insulin signaling in the embryonic elongation of C. elegans, a daf-2 loss of function seems to vary according to the allele ...
Read moreA lineage-resolved molecular atlas of C. elegans embryogenesis at single-cell resolution
A fundamental breakthrough in the understanding of development through the realization of the complete transcriptome of C. elegans, from the embryo to the terminal ...
Read moreThe size a ruling element in embryo to determine the fate and the function, suggesting cells are sensing size and can make decisions based on it
During early embryonic development polarity and asymmetric division are essential elements. In this paper Lars Hubatch et al. showed the significance of cell size in stem ...
Read moreHEART ON CHIP
Fibroblasts were grown and cultivated for 7 days AIMS → Improve IPSc derived cardiomyocytes differentiation → Establish a Duchenne's disease model on a chip → Combine electrical stimulations with biochemicals ...
Read moreFULLY DIFFERENTIATED SKIN ON CHIP
Reijnders CMA,...Gibbs S, Development of a Full-Thickness Human Skin Equivalent In Vitro Model Derived from TERT-Immortalized Keratinocytes and Fibroblasts, Tissue Eng Part A. 2015 Sep 1; ...
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