Heater/ Cooler for Phase Separation Pack

Mammalian cell, C. elegans, Yeast & In vitro construction

Liquid liquid phase separation, protein condensate, phase diagram

Compatible inverted and upright microscope

Ultrafast & precise temperature shift [10′ sec - 5 to 45°C]​

CherryTemp ultra-fast temperature controller allow you to:

  • Visualize the effect of temperature changes on your sample in the seconds’ timescale
  • In vivo imaging: membrane-less organelle dynamics, stress granules, IDPs
  • In vitro imaging: molecular assemblies, droplet formation
  • Compatible with a wide range of models: C. elegans, mammalian cells, in vitro protein assembly, purified protein, and more


  • Perform temperature shifts in less than 10 seconds with +/- 0.1 °C precision.
  • Dedicated protocols co-designed with our customers.
  • Easy handling, fast mounting on a microscope stage
  • HR microscopy compatible fits all upright and inverted microscopes.

publications featured cherrytemp

Some significative C. elegans articles :
1) Elbaum-Garfinkle et al., 2022, Liquid to solid transition of elastin condensates, PNAS
2) Elbaum-Garfinkle et al., 2020, Tunable multiphase dynamics of arginine and lysine liquid condensates, Nature Communications
3) Seydoux et al., 2019, A gel phase promotes condensation of liquid P granules in Caenorhabditis elegans embryos, Nature Structural & Molecular Biology
4) Kimble et al., 2019, Dynamics of Notch-Dependent Transcriptional Bursting in Its Native Context, Developmental Cell
5) Rosen et al., 2018, Nuclear Import Receptor Inhibits Phase Separation of FUS through Binding to Multiple Sites, Cell

More Phase Separation article published with our CherryTemp system here: Read more

free download ebook

complete guide to select the right temperature control system for live imaging

related resources

Liquid-liquid Phase Separation In Biology...
Introduction Membrane-less cellular compartments are characterized by liquid-phaseproperties and are important for sub-cellular organization...
Read more
Nuclear Import Receptor Inhibits Phase Separation Of FUS Through ...
FUS Liquid-Liquid Phase Separation What is Phase Separation with FUS? Cellular compartmentalization is essential for cell homeostasis. Cytop...
Read more

What Users Say About CherryTemp

" The Cherry Temp system was essential to acquiring some of our key data on the temperature-dependence of FUS phase separation. The system worked extremely well in these biochemical analyses. It was easy to use and robust, and required only small amounts of material. ”

Prof. Michael Rosen UT SOUTHWESTERN, USA

“CherryTemp is a one-of-a kind device for the study of thermosensitive mutants and cytoskeleton dynamics. Its flexibility makes it very easy to adapt to various geometries, from cells to tissue explants or even whole animals !”

Dr. Emmanuel Derivery MRC Lab of Molecular Biology, UK

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