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HEART ON CHIP

Fibroblasts were grown and cultivated for 7 days AIMS → Improve IPSc derived cardiomyocytes differentiation → Establish a Duchenne's disease model on a chip → Combine electrical stimulations with biochemicals ...

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FULLY DIFFERENTIATED SKIN ON CHIP

Reijnders CMA,...Gibbs S,  Development of a Full-Thickness Human Skin Equivalent In Vitro Model Derived from TERT-Immortalized Keratinocytes and Fibroblasts,  Tissue Eng Part A. 2015 Sep 1; ...

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LIVER BIOPSY ON CHIP

AIMS → Increase biopsies viability in long term culture → Imaging and biochemical quantification of drug effect → Interface blood vessel/hepatocyte → DILI assessment based on biochemical marker and morphometric read-out FEATURES → ...

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SPHEROID HUMAN KIDNEY CANCER ON CHIP

AIMS → Characterization and quantification of antimigration and antiproliferative effects of several molecules, mimicking acute exposure. → Detection of specific biomarkers FEATURES → Temperature : 37°C → Gas : normoxia 5% CO2 → Perfusion ...

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HUMAN BIOPSIES CULTURE

AIMS → Tumor(s) cells sequential exposure to compounds in different wells (drugs, antibodies, reagents) → Maintain automatic perfusion at a constant flow rate → Live optical readouts acquisition (fluorescence) FEATURES → Temperature ...

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LONG TERM KIDNEY TISSUE CULTURE

AIMS → Human kidney culture for 7 days → Automatic perfusion at a flow rate → Live optical readouts acquisition (fluorescence) FEATURES → Temperature : 37°C → Gas : normoxia, 5% CO2 → Perfusion mode : pulse → Culture ...

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