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Cell lineage-dependent chiral actomyosin flows drive cellular rearrangements in early development
The importance of chiral rotatory movements of the actomyosin cortex, involve in cellular rearrangements, during C. elegans embryo development. Stephan W. Grill et al. ...
Read moreRequirement for translocon-associated protein (TRAP) α in insulin biogenesis
Engineered C. elegans as a model organism for a better understanding of type 2 diabetes in humans. To better understand the mechanisms of peptide hormones, Xin Li ...
Read moreCentrosome Aurora A regulates RhoGEF ECT-2 localisation and ensures a single PAR-2 polarity axis in C. elegans embryos
Research has already shown a proper establishment of cell polarity is vital for several events during development stages and morphogenesis. This paper from Sukriti ...
Read moreHuman Microbiota and Microbioma : in vitro Culturing Approaches
The Human Microbiota present in the body Trillions of microorganisms habit the human body. Bacteria, fungi, viruses and archaea that are part of the human ...
Read moreKidney Biopsies and Precision Cut Slices for Advancing Research and Translational Medicine
The Kidney Biopsy – The Role in Diagnosis and Clinical Investigation The evolution of kidney biopsy techniques was instrumental in the advancement of nephrology, providing ...
Read moreSentinel Lymph Nodes (SLN) biopsies: clinical aspects
The lymphatic system is approximately omnipresent in the human body and present in most human tissues excluding cartilage, eye lens, epidemic, cornea, and bone ...
Read moreSkeletal Muscle Biopsy Beyond Histological Diagnosis: Ex-vivo Culturing and 3D Bioengineered model
Skeletal Muscle : Overview, Histology and Pathology Muscle tissue represent one of the four tissue in the human body with the epithelial tissue, connective tissue ...
Read moreOrganotypic brain slice culture : Organotypic brain slice culture : Prospect of a human model in preclinical drug development
Brain: No-human in-vivo model The human brain is one of the most convoluted organs. Contemporaneously,in-vivoand in-vitronon-human models are unraveling the mechanism of the complex ...
Read moreSkin Biopsies: In vitro Culturing Approaches for Precision Pharmacology in Skin Pathologies
The Skin – Beyond the Barrier The skin comprises±1.8m2, typically regarded as having a barrier to protect against environmental and xenobiological insults. However, skin ...
Read moreIntestinal Biopsies Beyond Histological Diagnosis: Ex-vivo Culturing and Precision Cut Slices for Precision Pharmacology
Intestine: Overview, Histology and Pathology The intestine is the largest part of the alimentary canal, which is part of the gastrointestinal tract (also called ...
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