Animal Testing Landscape 2025
About this white paper Animal testing has played a crucial role in medical advancements, leading to
Immuno
Melanoma Immunotherapy and Precision Medicine in the Era of Tumor Micro-Tissue Engineering: Where Are We Now and Where Are We Going?
Introduction Melanoma is clearly a complex disease with a high degree of heterogeneity and adaptability. Melanoma
Three-tissue microphysiological system for studying inflammatory responses in gut-liver Axis
Introduction The gut-liver axis is the bidirectional interaction that exists between the gut and its microbiota,
A Microfluidic 3D Endothelium-on-a-Chip Model to Study Transendothelial Migration of T Cells in Health and Disease
Introduction Microfluidic 3D Endothelium-on-a-Chip – The endothelium is a thin membrane that lines the heart and
The vascular niche in next generation microphysiological systems
Introduction The phrase ‘vascular niche’ refers to a region rich in blood arteries where endothelial cells
OOCHIP: Compartmentalized Microfluidic Perfusion System with Porous Barriers for Enhanced Cell-Cell Crosstalk in Organ-on-a-Chip (Ramadan et al)
Abstract (Ramadan et al) : Improved in vitro models of human organs for predicting drug efficacy, interactions, and
Breast Biopsy: Advantages and Challenges for Ex Vivo Culturing in the Age of Personalized Medicine
Breast Biopsies and Breast Cancer Breast cancer is the most common female cancer worldwide with the
In Vitro Immune Organs-on-Chip for Drug Development
Organs-on-Chip for Drug Development A drug should pass the preclinical evaluation phase to be FDA-approved. This
Immune Checkpoint Modulators: An Emerging Antiglioma Armamentarium
Immune Checkpoint Modulators as an emerging therapy Through this paper, Kim and colleagues highlight the way
Checkpoint modulation – A new way to direct the immune system against renal cell carcinoma
Immune checkpoint modulation in renal cell carcinoma In this paper, Bedke and colleague highlight the way that patients treated for
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