Adipose Tissue Organoids: Protocols, Applications & Current Limitations
Adipose tissue organoid technology is reshaping metabolic research. From scaffold-free spheroids to hydrogel-based 3D adipose tissue
Liver
Understanding Adipose Tissue: A Key to Drug Discovery in Metabolic Disorders
What Does Adipose Tissue Do? Adipose tissue is more than a fat storage site, it’s a
Brown vs White Adipose Tissue: What is at Stake for Pharma
As the global obesity crisis intensifies, the functional contrast between brown adipose tissue and white adipose
In Vitro Adipose Tissue Models: Organoids, Organs-on-Chip & Next-Generation Platforms
Modern drug discovery is shifting from “one-size-fits-all” animal models toward new-approach methodologies (NAMs) that capture human-specific
Animal Testing Landscape 2025
About this white paper Animal testing has played a crucial role in medical advancements, leading to
A versatile microfluidic tool for the 3D culture of HepaRG cells seeded at various stages of differentiation
Introduction Animal models and two-dimensional (2D) cell cultures frequently fail to replicate human drug metabolism and liver
Three-tissue microphysiological system for studying inflammatory responses in gut-liver Axis
Introduction The gut-liver axis is the bidirectional interaction that exists between the gut and its microbiota,
Liver microphysiological platforms for drug metabolism applications
Introduction Liver microphysiological platforms for drug metabolism applications are the need of the hour to fix the exorbitant
Restorative effect of adipose tissue-derived stem cells on impaired hepatocytes through Notch signaling in non-alcoholic steatohepatitis mice (Ishida et al, 2021)
Introduction Adipose tissue-derived stem cells (ADSCs) are mesenchymal stem cells (MSCs) that are obtained from abundant
Experimental liver models: from cell culture techniques to microfluidic organs-on-chip (Polidoro et al, 2021)
Introduction The Organ-on-a-Chip (OOAC) is a leading organ biomimetic (POB) device based on a microfluidic chip in the
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