A versatile microfluidic tool for the 3D culture of HepaRG cells seeded at various stages of differentiation
Introduction Animal models and two-dimensional (2D) cell cultures frequently fail to replicate human drug metabolism and liver
Get a better understanding and prediction for pre-clinical drug trials
Allowing comprehension and predicting of human responses earlier, while also offering ethical alternatives to animal testing.
Introduction Animal models and two-dimensional (2D) cell cultures frequently fail to replicate human drug metabolism and liver
Introduction The gut-liver axis is the bidirectional interaction that exists between the gut and its microbiota,
Introduction Liver microphysiological platforms for drug metabolism applications are the need of the hour to fix the exorbitant
Introduction Adipose tissue-derived stem cells (ADSCs) are mesenchymal stem cells (MSCs) that are obtained from abundant
Introduction The Organ-on-a-Chip (OOAC) is a leading organ biomimetic (POB) device based on a microfluidic chip in the
Introduction SARS-CoV-2 is the virus that caused the COVID-19 pandemic and its devastating effects on global
The Liver: Overview, Histology and Pathology The liver (Fig. 1) is the largest organ in the
Introduction Drug induced liver injury (DILI)is one of the major reasons of drug attrition and it
Introduction The liver is a fundamental organ for human life. It is responsible for macromolecules (carbohydrates,
Why a liver on a chip? The liver is part of the digestive tract, and the
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