New approaches methodologies for hormone receptor-positive (Luminal A/B) breast cancer
Luminal A and B breast cancers, collectively known as hormone receptor–positive (HR+) disease, represent the most
Scientific Notes
SVF vs ADSC for 3D adipose culture: What source to use?
In this discussion, we investigate the optimal cell source for constructing 3D adipose models, predicated on
Applications of HER2+ organoids and NAMs to study breast cancer
HER2-positive breast cancer represents about one quarter of breast malignancies and is driven by amplification of
Triple-Negative Breast Cancer and the Application of Breast Cancer Organoid Models
Triple-negative breast cancer (TNBC) is a distinct pathological subtype defined by the absence of estrogen receptor
10 Groundbreaking Studies Using 3D Adipose Tissue Models (2020-2025)
Obesity and its related metabolic diseases, such as type 2 diabetes, represent a growing global health
From 2D to 3D: Restoring in vitro liver models functions
In our previous article, we outlined the main in vitro liver models, immortalized cell lines such
In vitro liver models in drug discovery: Main models, advantages and use cases
In vitro liver models are central to drug discovery and toxicology, enabling controlled evaluation of metabolism,
Top 10 Breakthrough Studies Using Liver Organoids and Liver-on-Chip for Drug Discovery (2024-2025)
Liver disease and drug-induced liver injury remain critical challenges in medicine and pharmaceutical development, demanding models
Liver-on-Chip Platforms: Recreating Human Physiology for Predictive Drug Development
Re-Engineering the Liver Microenvironment In the first article of this series, we discussed the limitations of
Liver Organoids in Drug Discovery: 3D Cell Culture Models Transforming Toxicity Testing and Personalized Medicine
The liver organoid is transforming how researchers approach drug discovery and safety testing. As miniature, three-dimensional
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