Liver-on-Chip Platforms: Recreating Human Physiology for Predictive Drug Development
Re-Engineering the Liver Microenvironment In the first article of this series, we discussed the limitations of
Scientific Notes
Liver Organoids in Drug Discovery: 3D Cell Culture Models Transforming Toxicity Testing and Personalized Medicine
The liver organoid is transforming how researchers approach drug discovery and safety testing. As miniature, three-dimensional
Organoids for Lipid Metabolism: Organoid and Organ-on-Chip Models in Metabolic Disease Research
Understanding how the body processes fats is central to tackling obesity, type 2 diabetes, and fatty
10 key studies on breast cancer research powered by New Approach Methodologies (2024–2025)
Breast cancer remains the most common malignancy in women worldwide, and progress in treatment increasingly depends
What’s new in breast cancer research? – July-August 2025
Breast cancer is the second cancer-related cause of death in women worldwide, therefore it is no
How breast cancer organoids can accelerate ongoing clinical trials and mAb/ADC development under FDA’s animal-reduction roadmap
Introduction Microphysiological systems (MPS) are fast becoming a cornerstone of FDA-aligned non-clinical strategy, especially when paired
Organoid and artificial intelligence in breast cancer research
Introduction Organoid and artificial intelligence approaches are central to the FDA’s roadmap for reducing animal use
Adipose tissue and breast cancer: decoding proximal crosstalk in 3D model
Introduction Adipose tissue-breast cancer crosstalk is emerging as a key driver of tumor initiation, progression, and
3D Breast Cancer Microenvironment: From Organoids to Organ‑on‑Chip for Understanding the TME
Introduction Following our articles on how breast cancer organoids and breast‑cancer‑on‑chip platforms expand beyond conventional 2D and
2D vs 3D breast cancer models: Patient‑derived organoids for tumor modeling
3D breast cancer models are rapidly redefining how we investigate the world’s deadliest malignancy in women,
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