From 2D to 3D: Restoring in vitro liver models functions
In our previous article, we outlined the main in vitro liver models, immortalized cell lines such
3D Cell Culture
In vitro liver models in drug discovery: Main models, advantages and use cases
In vitro liver models are central to drug discovery and toxicology, enabling controlled evaluation of metabolism,
Top 10 Breakthrough Studies Using Liver Organoids and Liver-on-Chip for Drug Discovery (2024-2025)
Liver disease and drug-induced liver injury remain critical challenges in medicine and pharmaceutical development, demanding models
Liver-on-Chip Platforms: Recreating Human Physiology for Predictive Drug Development
Re-Engineering the Liver Microenvironment In the first article of this series, we discussed the limitations of
Liver Organoids in Drug Discovery: 3D Cell Culture Models Transforming Toxicity Testing and Personalized Medicine
The liver organoid is transforming how researchers approach drug discovery and safety testing. As miniature, three-dimensional
Organoids for Lipid Metabolism: Organoid and Organ-on-Chip Models in Metabolic Disease Research
Understanding how the body processes fats is central to tackling obesity, type 2 diabetes, and fatty
10 key studies on breast cancer research powered by New Approach Methodologies (2024–2025)
Breast cancer remains the most common malignancy in women worldwide, and progress in treatment increasingly depends
What’s new in breast cancer research? – July-August 2025
Breast cancer is the second cancer-related cause of death in women worldwide, therefore it is no
How breast cancer organoids can accelerate ongoing clinical trials and mAb/ADC development under FDA’s animal-reduction roadmap
Introduction Microphysiological systems (MPS) are fast becoming a cornerstone of FDA-aligned non-clinical strategy, especially when paired
Organoid and artificial intelligence in breast cancer research
Introduction Organoid and artificial intelligence approaches are central to the FDA’s roadmap for reducing animal use
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