Facilitating implementation of organs-on-chips by open platform technology
Introduction Many Organ-on-Chip platforms are still not robust for all cell types, are not reproducible from experiment to
Microphysiological System
Pumpless, modular, microphysiological systems enabling tunable perfusion for long-term cultivation of endothelialized lumens
Introduction The authors present a simple and modular Microphysiological system without the use of complex components consisting of
Three-tissue microphysiological system for studying inflammatory responses in gut-liver Axis
Introduction The gut-liver axis is the bidirectional interaction that exists between the gut and its microbiota,
Organ-on-Chips for Studying Tissue Barriers: Standard Techniques and a Novel Method for Including Porous Membranes Within Microfluidic Devices
Introduction Organ-on-Chips for Studying Tissue Barriers – Disruption of cell-formed tissue barriers is an essential part of
A Microfluidic 3D Endothelium-on-a-Chip Model to Study Transendothelial Migration of T Cells in Health and Disease
Introduction Microfluidic 3D Endothelium-on-a-Chip – The endothelium is a thin membrane that lines the heart and
3D Microphysiological System- Vascularized Tissue Constructs for Regenerative Medicine
Introduction Human vascular microphysiological systems (MPS) represent promising three-dimensional in vitro models of normal and diseased vascular tissue.
Organ-on-a-Chip: A New Paradigm for Drug Development
Introduction Organ-on-a-Chip is a potential, multidisciplinary method for in-vitro modeling of disease, drug screening, and precision medicine
A Review of Biomaterials and Scaffold Fabrication for Organ-on-a-Chip Systems
Introduction Biomaterial scaffold like the extracellular matrix (ECM) is the non-cellular component of an organ on
The vascular niche in next generation microphysiological systems
Introduction The phrase ‘vascular niche’ refers to a region rich in blood arteries where endothelial cells
Advanced Models of Human Muscle Differentiation: 3D Cultures, Organoids & Beyond
Introduction The organization and function of living muscle tissues cannot be fully recapitulated by typical two-dimensional
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