Organ-on-a-Chip: A New Paradigm for Drug Development
Introduction Organ-on-a-Chip is a potential, multidisciplinary method for in-vitro modeling of disease, drug screening, and precision medicine
Microphysiological System
A Review of Biomaterials and Scaffold Fabrication for Organ-on-a-Chip Systems
Introduction Biomaterial scaffold like the extracellular matrix (ECM) is the non-cellular component of an organ on
The vascular niche in next generation microphysiological systems
Introduction The phrase ‘vascular niche’ refers to a region rich in blood arteries where endothelial cells
Advanced Models of Human Muscle Differentiation: 3D Cultures, Organoids & Beyond
Introduction The organization and function of living muscle tissues cannot be fully recapitulated by typical two-dimensional
Kidney Organoids and Microphysiological Kidney Chip Models to Accelerate Drug Development and Reduce Animal Testing
Introduction Kidney Organoid and Microphysiological Kidney Chip Models, both have their own unique advantages and deficiencies.
Beyond Polydimethylsiloxane (PDMS): Alternative Materials for Fabrication of Organ-on-a-Chip Devices and Microphysiological Systems
Introduction DMS, often known as dimethylpolysiloxane or dimethicone, is a silicone polymer. There are various uses
Pharmacokinetics-On-a-Chip: In Vitro Microphysiological Models for Emulating of Drugs ADME
Introduction Microphysiological systems may predict drug pharmacokinetics, effectiveness and toxicity more accurately in humans. Pharmacokinetics-On-a-Chip: In Vitro Microphysiological Models
Liver microphysiological platforms for drug metabolism applications
Introduction Liver microphysiological platforms for drug metabolism applications are the need of the hour to fix the exorbitant
Adipocyte heterogeneity underlying adipose tissue functions
Introduction Adipose tissue functions are not only to store energy, it also governs the metabolism of
Perilipin 5 links mitochondrial uncoupled respiration in brown fat to healthy white fat remodeling and systemic glucose tolerance (Gallardo-Montejano et al, 2021)
Introduction According to a recent study headed by UT Southwestern researchers, increasing a protein contained in
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