Kidney Organoids and Microphysiological Kidney Chip Models to Accelerate Drug Development and Reduce Animal Testing
Introduction Kidney Organoid and Microphysiological Kidney Chip Models, both have their own unique advantages and deficiencies.
Microphysiological System
Beyond Polydimethylsiloxane (PDMS): Alternative Materials for Fabrication of Organ-on-a-Chip Devices and Microphysiological Systems
Introduction DMS, often known as dimethylpolysiloxane or dimethicone, is a silicone polymer. There are various uses
Pharmacokinetics-On-a-Chip: In Vitro Microphysiological Models for Emulating of Drugs ADME
Introduction Microphysiological systems may predict drug pharmacokinetics, effectiveness and toxicity more accurately in humans. Pharmacokinetics-On-a-Chip: In Vitro Microphysiological Models
Liver microphysiological platforms for drug metabolism applications
Introduction Liver microphysiological platforms for drug metabolism applications are the need of the hour to fix the exorbitant
Adipocyte heterogeneity underlying adipose tissue functions
Introduction Adipose tissue functions are not only to store energy, it also governs the metabolism of
Perilipin 5 links mitochondrial uncoupled respiration in brown fat to healthy white fat remodeling and systemic glucose tolerance (Gallardo-Montejano et al, 2021)
Introduction According to a recent study headed by UT Southwestern researchers, increasing a protein contained in
Rebuilding the Vascular Network: In vivo and in vitro Approaches (Meng et al, 2021)
Introduction The vascular network carries the transportation of materials and nutrients as the fluid delivery mechanism
Experimental liver models: from cell culture techniques to microfluidic organs-on-chip (Polidoro et al, 2021)
Introduction The Organ-on-a-Chip (OOAC) is a leading organ biomimetic (POB) device based on a microfluidic chip in the
Binding of the SARS-CoV-2 Spike Protein to the Asialoglycoprotein Receptor on Human Primary Hepatocytes and Immortalized Hepatocyte-Like Cells by Confocal Analysis (Collins DP et al, 2021)
Introduction SARS-CoV-2 is the virus that caused the COVID-19 pandemic and its devastating effects on global
Insulin action in adipocytes, adipose remodeling, and systemic effects (Santoro et al, 2021)
Introduction (Santoro et al) recognizes the essential importance adipocytes which react exquisitely to insulin have played in determining the mechanisms
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