Tumor Hypoxia and Metastasis
Context Solid tumors are characterized by areas of hypoxic tissue heterogeneously distributed inside the tumor mass.
3D Cell Culture
Tumor microenvironment (TME)
The tumor microenvironment (TME) is a complex biochemical network that includes multiple factors surrounding tumor cells,
3D cell culture and anticancer drug testing
Efficacity and toxicity of candidate anticancer drugs on 3D cell culture model has been much lower
In Vitro Immune Organs-on-Chip for Drug Development
Organs-on-Chip for Drug Development A drug should pass the preclinical evaluation phase to be FDA-approved. This
Nanoscopy to improve drug screening and liver fenestrations
Introduction Drug induced liver injury (DILI)is one of the major reasons of drug attrition and it
Liver function and liver on a chip
Introduction The liver is a fundamental organ for human life. It is responsible for macromolecules (carbohydrates,
Immune Checkpoint Modulators: An Emerging Antiglioma Armamentarium
Immune Checkpoint Modulators as an emerging therapy Through this paper, Kim and colleagues highlight the way
Checkpoint modulation – A new way to direct the immune system against renal cell carcinoma
Immune checkpoint modulation in renal cell carcinoma In this paper, Bedke and colleague highlight the way that patients treated for
Immune Check Point Modulator in Cancer Therapy
Immune Checkpoint Modulators Summary Immune Checkpoint modulators are new promising therapies that specifically target the ability
Immuno-oncology Trial Endpoints: Capturing Meaningful Activity
Introduction In this paper, Anagnostou and colleagues “discuss endpoints used in I-O trials to date and potential
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