3D Cell Culture

Tumor Hypoxia and Metastasis

Context Solid tumors are characterized by areas of hypoxic tissue heterogeneously distributed inside the tumor mass.

The tumor microenvironment (TME) is a complex biochemical network that includes multiple factors surrounding tumor cells,

Efficacity and toxicity of candidate anticancer drugs on 3D cell culture model has been much lower

Organs-on-Chip for Drug Development A drug should pass the preclinical evaluation phase to be FDA-approved. This

Introduction Drug induced liver injury (DILI)is one of the major reasons of drug attrition and it

Introduction The liver is a fundamental organ for human life. It is responsible for macromolecules (carbohydrates,

Immune Checkpoint Modulators as an emerging therapy Through this paper, Kim and colleagues highlight the way

Immune checkpoint modulation in renal cell carcinoma In this paper, Bedke and colleague highlight the way that patients treated for

Immune Checkpoint Modulators Summary Immune Checkpoint modulators are new promising therapies that specifically target the ability

Introduction In this paper, Anagnostou and colleagues “discuss endpoints used in I-O trials to date and potential