Three-tissue microphysiological system for studying inflammatory responses in gut-liver Axis
Introduction The gut-liver axis is the bidirectional interaction that exists between the gut and its microbiota,
Liver
Liver microphysiological platforms for drug metabolism applications
Introduction Liver microphysiological platforms for drug metabolism applications are the need of the hour to fix the exorbitant
Restorative effect of adipose tissue-derived stem cells on impaired hepatocytes through Notch signaling in non-alcoholic steatohepatitis mice (Ishida et al, 2021)
Introduction Adipose tissue-derived stem cells (ADSCs) are mesenchymal stem cells (MSCs) that are obtained from abundant
Experimental liver models: from cell culture techniques to microfluidic organs-on-chip (Polidoro et al, 2021)
Introduction The Organ-on-a-Chip (OOAC) is a leading organ biomimetic (POB) device based on a microfluidic chip in the
Binding of the SARS-CoV-2 Spike Protein to the Asialoglycoprotein Receptor on Human Primary Hepatocytes and Immortalized Hepatocyte-Like Cells by Confocal Analysis (Collins DP et al, 2021)
Introduction SARS-CoV-2 is the virus that caused the COVID-19 pandemic and its devastating effects on global
Liver Biopsies Beyond Histological Diagnosis: Ex-vivo Culturing and Precision Cut Slices for Precision Pharmacology
The Liver: Overview, Histology and Pathology The liver (Fig. 1) is the largest organ in the
Nanoscopy to improve drug screening and liver fenestrations
Introduction Drug induced liver injury (DILI)is one of the major reasons of drug attrition and it
Liver function and liver on a chip
Introduction The liver is a fundamental organ for human life. It is responsible for macromolecules (carbohydrates,
Liver on a chip state of the art
Why a liver on a chip? The liver is part of the digestive tract, and the
The Complexity Behind the 3D Cell Cultures: the 3D Liver Cell Culture Case
Introduction Once it is clear how to deal with 3D cell cultures it is time to
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