Melanoma Immunotherapy and Precision Medicine in the Era of Tumor Micro-Tissue Engineering: Where Are We Now and Where Are We Going?
Introduction Melanoma is clearly a complex disease with a high degree of heterogeneity and adaptability. Melanoma
Scientific Notes
Microfluidic organ-on-chip system for multi-analyte monitoring of metabolites in 3D cell cultures
Introduction The researchers created a microfluidic organ-on-chip solution with integrated electrochemical microsensor arrays enabling compartmentalized matrix-based organoid culture
A versatile microfluidic tool for the 3D culture of HepaRG cells seeded at various stages of differentiation
Introduction Animal models and two-dimensional (2D) cell cultures frequently fail to replicate human drug metabolism and liver
Probing Insulin Sensitivity with Metabolically Competent Human Stem Cell-Derived White Adipose Tissue Microphysiological Systems
Introduction Adipose Tissue is very versatile and essential for studies related to Obesity and Diabetes, however, the high buoyancy, fragility,
A new microfluidic method enabling the generation of multi-layered tissues-on-chips using skin cells as a proof of concept
Introduction The state of the art for tissues-on-chips using skin cells had been lacking for a long time
Facilitating implementation of organs-on-chips by open platform technology
Introduction Many Organ-on-Chip platforms are still not robust for all cell types, are not reproducible from experiment to
Pumpless, modular, microphysiological systems enabling tunable perfusion for long-term cultivation of endothelialized lumens
Introduction The authors present a simple and modular Microphysiological system without the use of complex components consisting of
Three-tissue microphysiological system for studying inflammatory responses in gut-liver Axis
Introduction The gut-liver axis is the bidirectional interaction that exists between the gut and its microbiota,
Low-cost rapid prototyping and assembly of an open microfluidic device for a 3D vascularized organ-on-a-chip
Introduction In vitro generation of perfusable 3D microvessels is an important goal for tissue engineering and
Co-culture With Human Breast Adipocytes Differentially Regulates Protein Abundance in Breast Cancer Cells
Introduction In postmenopausal women, fat mass and adipose-tissue mass (see Human Breast Adipocytes) are closely linked to obesity
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