Isolation, Integration, and Culture of Human Mature Adipocytes Leveraging Organ-on-Chip Technology
Introduction Obesity and obesity-related co-morbidities are on the rise globally, necessitating the development of novel treatments. White
3D Cell Culture
A Microfluidic 3D Endothelium-on-a-Chip Model to Study Transendothelial Migration of T Cells in Health and Disease
Introduction Microfluidic 3D Endothelium-on-a-Chip – The endothelium is a thin membrane that lines the heart and
3D Microphysiological System- Vascularized Tissue Constructs for Regenerative Medicine
Introduction Human vascular microphysiological systems (MPS) represent promising three-dimensional in vitro models of normal and diseased vascular tissue.
Organ-on-a-Chip: A New Paradigm for Drug Development
Introduction Organ-on-a-Chip is a potential, multidisciplinary method for in-vitro modeling of disease, drug screening, and precision
A Review of Biomaterials and Scaffold Fabrication for Organ-on-a-Chip Systems
Introduction Biomaterial scaffold like the extracellular matrix (ECM) is the non-cellular component of an organ on
Adipocyte-Endothelium Crosstalk in Obesity
Introduction The supporting vasculature is critical to the development of Adipose Tissue (AT) engineered models. Although it is
The vascular niche in next generation microphysiological systems
Introduction The phrase ‘vascular niche’ refers to a region rich in blood arteries where endothelial cells
Organ-on-chip applications in drug discovery: an end-user perspective
Introduction Organ-on-a-chip is regarded as a key new technology for research and drug development because it
Advanced Models of Human Muscle Differentiation: 3D Cultures, Organoids & Beyond
Introduction The organization and function of living muscle tissues cannot be fully recapitulated by typical two-dimensional
Kidney Organoids and Microphysiological Kidney Chip Models to Accelerate Drug Development and Reduce Animal Testing
Introduction Kidney Organoid and Microphysiological Kidney Chip Models, both have their own unique advantages and deficiencies.
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