Scientific notes

Imaging of mitochondria positioning on microtubule using fast temperature regulation

Abstract of mmb1p Binds Mitochondria to Dynamic Microtubules

 Mitochondria form a dynamic tubular network within the cell. Proper mitochondria movement and distribution are critical for their localized function in cell metabolism, growth, and survival. In mammalian cells, mechanisms of mitochondria positioning appear dependent on the microtubule cytoskeleton, with kinesin or dynein motors carrying mitochondria as cargos and distributing them throughout the microtubule network. Interestingly, the timescale of microtubule dynamics occurs in seconds, and the timescale of mitochondria distribution occurs in minutes. How does the cell couple these two time constants?

Video extracted from the publication. 

How to culture vascularized & immunocompetent 3D models in a standard Multiwell

References

https://www.sciencedirect.com/science/article/pii/S0960982211007822Chuanhai Fu, Deeptee Jain, Judite Costa, Guilhem Velve-Casquillas, Phong T. Tran, mmb1p Binds Mitochondria to Dynamic Microtubules, Current Biology, Volume 21, Issue 17, 2011, Pages 1431-1439,

Related Posts

From an organ on a chip to a body on a chip...
Scaling up organs on a chip to get a functional body on a chip Recent innovations in microfluidic technologies have produced organ on a chi...
Read more
3d-cell-culture-intestinal-anatomy-histology
Liver microphysiological platforms for drug metabolism applicatio...
Introduction Liver microphysiological platforms for drug metabolism applications are the need of the hour to fix the exorbitant costs of d...
Read more
Tumor Hypoxia and Metastasis...
Context Solid tumors are characterized by areas of hypoxic tissue heterogeneously distributed inside the tumor mass. Hypoxia triggers tumor ...
Read more

get in touch

Get the best insights about Cherry Biotech by Email Let’s stay in touch!
As part of our commercial prospecting, we may need to process your personal data. For more information, please consult our Privacy Policy