Kidney Organoids and Microphysiological Kidney Chip Models to Accelerate Drug Development and Reduce Animal Testing
Introduction Kidney Organoid and Microphysiological Kidney Chip Models, both have their own unique advantages and deficiencies.
Scientific Notes
Beyond Polydimethylsiloxane (PDMS): Alternative Materials for Fabrication of Organ-on-a-Chip Devices and Microphysiological Systems
Introduction DMS, often known as dimethylpolysiloxane or dimethicone, is a silicone polymer. There are various uses
Pharmacokinetics-On-a-Chip: In Vitro Microphysiological Models for Emulating of Drugs ADME
Introduction Microphysiological systems may predict drug pharmacokinetics, effectiveness and toxicity more accurately in humans. Pharmacokinetics-On-a-Chip: In Vitro Microphysiological Models
Liver microphysiological platforms for drug metabolism applications
Introduction Liver microphysiological platforms for drug metabolism applications are the need of the hour to fix the exorbitant
Adipose Tissue – Endothelial Cell Interactions in Obesity – Induced Endothelial Dysfunction
Introduction Adipose tissue progenitor cells directly interact with endothelial cells to induce vascular network formation. Adipose
Adipocyte heterogeneity underlying adipose tissue functions
Introduction Adipose tissue functions are not only to store energy, it also governs the metabolism of
Restorative effect of adipose tissue-derived stem cells on impaired hepatocytes through Notch signaling in non-alcoholic steatohepatitis mice (Ishida et al, 2021)
Introduction Adipose tissue-derived stem cells (ADSCs) are mesenchymal stem cells (MSCs) that are obtained from abundant
Perilipin 5 links mitochondrial uncoupled respiration in brown fat to healthy white fat remodeling and systemic glucose tolerance (Gallardo-Montejano et al, 2021)
Introduction According to a recent study headed by UT Southwestern researchers, increasing a protein contained in
Rebuilding the Vascular Network: In vivo and in vitro Approaches (Meng et al, 2021)
Introduction The vascular network carries the transportation of materials and nutrients as the fluid delivery mechanism
Experimental liver models: from cell culture techniques to microfluidic organs-on-chip (Polidoro et al, 2021)
Introduction The Organ-on-a-Chip (OOAC) is a leading organ biomimetic (POB) device based on a microfluidic chip in the
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